The Importance of Microplate Readers in 3D Biology

The arrival of 3D biology represents a paradigm shift in disease modeling and drug development. Traditional in vitro 2D plate-based cell models are being replaced by 3D cell model organoid systems which better represent in vivo physiological traits and biological processes of native tissue. Organoids provide cell and tissue-type insight that aims to accelerate the pace of disease research and drug screening.

Microplate readers play a critical role in 3D biology workflows. The article explores a recent study titled “A walkaway solution for assessing drug effects in patient-derived colorectal cancer organoids” describing the use of the SpectraMax® iD5 Multi-Mode microplate reader in cancer organoid cell viability assays.