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The SCIEX API 5000 is a highly sensitive triple quadrupole mass spectrometer designed primarily for quantitative analysis in complex matrices, making it a cornerstone in pharmaceutical, biochemical, and environmental testing laboratories. This system is renowned for its robustness and high performance, particularly in detecting low-level analytes under challenging conditions. A key quantifiable feature of the SCIEX API 5000 is its exceptional sensitivity, with a lower limit of quantification (LLOQ) up to 10 times better than its contemporaries. This allows for precise measurement of trace levels of drugs, metabolites, and other chemicals. The mass range of the API 5000 extends from 5 to 1,250 m/z (mass-to-charge ratio), enabling the analysis of a broad spectrum of molecules. It also features an ionization source that can be easily switched between Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) modes, broadening its applicability across various types of samples and analytical conditions. Further, the SCIEX API 5000 is equipped with advanced software that supports intuitive operation, data handling, and detailed reporting. This includes the ability to perform complex data analyses such as MRM (Multiple Reaction Monitoring), which is essential for the high-throughput quantification and validation of samples in regulated environments. Its sturdy construction and reliable performance make it a preferred choice for laboratories requiring high accuracy and repeatability in quantitative mass spectrometry.
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