STRmix DBLR™ v1.4

STRmix DBLR™ v1.4 is the latest release from the forensic software development team known for STRmix™. This version is designed to enhance kinship analysis capabilities and facilitate the rapid calculation of millions of DNA likelihood ratios (LRs). DBLR™ v1.4 integrates seamlessly with STRmix™ to allow forensic laboratories to effectively analyze mixed DNA profiles that were previously considered too complex or degraded.

Key Features of STRmix DBLR™ v1.4:

• Integration with STRmix™: Enables combined use with STRmix™ to analyze complex DNA samples.
• Kinship Analysis Enhancements: Improves the calculation of kinship likelihood ratios by incorporating the sex of pedigree members in the calculations, a feature not available in previous versions.
• Amelogenin Locus Inclusion: Allows the inclusion of the Amelogenin locus in likelihood ratio calculations across all modules, enhancing the accuracy of sex-related genetic analysis.
• Applications: Facilitates database searches, visualization of DNA mixture evidence, mixture-to-mixture matches, common donor determinations, and evaluations of potential family relationships.

Usability and Applications: DBLR™ v1.4 is used in forensic laboratories for tasks such as identifying human remains, assisting in cold case investigations, and saving significant time in manual kinship calculations. It supports a variety of forensic applications by providing tools for direct comparison of DNA mixtures to known profiles, constructing complex pedigrees, and modeling linkage, mutation, and population stratification.

Adoption and Impact: This software is part of a suite that includes STRmix™ and FaSTR™ DNA, which are used in over 530,000 criminal cases worldwide. STRmix™ is employed by 85 federal, state, local, and private organizations in the US, and 27 forensic laboratories internationally.